Asleep
From Titan's Teeth
A character who is asleep is resting and Helpless.
An asleep character can be awoken by an ally as a standard action (a special application of the aid another action) or from being wounded.
While asleep, a character takes a –10 penalty on Perception checks and cannot attempt Perception checks that rely on vision, but she can otherwise attempt reactive Perception checks to notice changes in her environment that do not rely on sight.
For instance, a sleeping character can attempt a Perception check to hear a loud noise, smell a terrible odor, or sense a creature burrowing in the earth beneath her. If a sleeping character succeeds at a Perception check to notice such a change, she automatically awakens.
Helpless
A helpless character is paralyzed, held, bound, sleeping, unconscious, or otherwise completely at an opponent’s mercy.
A helpless target is treated as having a Dexterity of 0 (–5 modifier).
Melee attacks against a helpless target get a +4 bonus (equivalent to attacking a prone target).
Ranged attacks get no special bonus against helpless targets.